RAS DOWNSTREAM EFFECTOR GGCT ALLEVIATES ONCOGENIC STRESS

Ras Downstream Effector GGCT Alleviates Oncogenic Stress

Summary: How cells adapt to oncogenic transformation-associated cellular stress and become fully transformed is still unknown.Here we identified a novel GGCT-regulated glutathione (GSH)-reactive oxygen species (ROS) metabolic pathway in oncogenic stress alleviation.We identified GGCT as a target of oncogenic Ras and that it is required for oncogeni

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Microstructure-based simulation on the mechanical behavior of particle reinforced metal matrix composites with varying particle characteristics

The mechanical performance of metal matrix composites Guitar Stands strengthened with particles is predominantly contingent upon the attributes of the incorporated particles.Attaining the optimal particle size, morphology, and interfacial bonding within the composites is paramount for improving the comprehensive properties.In this study, an experim

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