Ras Downstream Effector GGCT Alleviates Oncogenic Stress
Summary: How cells adapt to oncogenic transformation-associated cellular stress and become fully transformed is still unknown.Here we identified a novel GGCT-regulated glutathione (GSH)-reactive oxygen species (ROS) metabolic pathway in oncogenic stress alleviation.We identified GGCT as a target of oncogenic Ras and that it is required for oncogeni